TTD | Drug: D0E9DE

Drug General Information
Drug ID	D0E9DE
Former ID	DIB018986
Drug Name	BMS compound 4c
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[541194]
Structure		Download 2D MOL
Formula	C24H21F3N4OS
InChI	InChI=1S/C24H21F3N4OS/c1-23(2,3)17-7-4-5-9-19(17)32-20-18(8-6-14-28-20)29-22-31-30-21(33-22)15-10-12-16(13-11-15)24(25,26)27/h4-14H,1-3H3,(H,29,31)
InChIKey	ROIKEXLVELZTIZ-UHFFFAOYSA-N
PubChem Compound ID	71655433
PubChem Substance ID	163818326, 174512212, 175448129, 178102524
Target and Pathway
Target(s)	P2Y purinoceptor 1	Target Info	Antagonist	[532349]
KEGG Pathway	Rap1 signaling pathway
	Neuroactive ligand-receptor interaction
	Platelet activation
Reactome	G alpha (q) signalling events
	P2Y receptors
	ADP signalling through P2Y purinoceptor 1
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Signal amplification
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 541194	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5901).
Ref 532349	New azole antagonists with high affinity for the P2Y(1) receptor. Bioorg Med Chem Lett. 2013 Jun 15;23(12):3519-22.

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Drug Information