Drug Information

Drug General Information
Drug ID
D0E5HC
Former ID
DNC003343
Drug Name
3-(5-methoxy-1H-indol-3-yl)propanoic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551374]
Structure
Download
2D MOL

3D MOL
Formula
C12H13NO3
Canonical SMILES
COC1=CC2=C(C=C1)NC=C2CCC(=O)O
InChI
1S/C12H13NO3/c1-16-9-3-4-11-10(6-9)8(7-13-11)2-5-12(14)15/h3-4,6-7,13H,2,5H2,1H3,(H,14,15)
InChIKey
ZLSZCJIWILJKMR-UHFFFAOYSA-N
PubChem Compound ID
181137
PubChem Substance ID
3433908, 4513020, 8112355, 10259373, 11177116, 11217585, 17476508, 24300031, 25630112, 33503968, 47487473, 57244469, 77899824, 89128767, 92236459, 99247359, 99444194, 104433802, 104847627, 117676131, 124663390, 125603589, 129920970, 135160777, 135586904, 137044037, 139622370, 143415823, 143802578, 160968790, 162516459, 169571045, 179179637, 223926267, 229078986, 249804210, 251875984, 252456062, 252471783
Target and Pathway
Target(s) Peroxisome proliferator activated receptor gamma Target Info Inhibitor [551374]
KEGG Pathway PPAR signaling pathway
AMPK signaling pathway
Osteoclast differentiation
Huntington's disease
Pathways in cancer
Transcriptional misregulation in cancer
Thyroid cancer
NetPath Pathway IL1 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
Leptin Signaling Pathway
PANTHER Pathway CCKR signaling map ST
Pathway Interaction Database Noncanonical Wnt signaling pathway
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
Signaling events mediated by HDAC Class I
RXR and RAR heterodimerization with other nuclear receptor
Regulation of retinoblastoma protein
Reactome PPARA activates gene expression
Transcriptional regulation of white adipocyte differentiation
Nuclear Receptor transcription pathway
WikiPathways Wnt Signaling Pathway Netpath
Nuclear Receptors in Lipid Metabolism and Toxicity
Differentiation of white and brown adipocyte
Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Transcriptional Regulation of White Adipocyte Differentiation
Adipogenesis
SREBP signalling
Nuclear Receptors
References
Ref 551374The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
Ref 551374The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.