Drug General Information
Drug ID
D0E3SX
Former ID
DIB012275
Drug Name
SCH-1359113
Synonyms
SCH-1341030; SCH-1359113; SCH-1682496; SCH-745966; SCH-747123; SCH-785532; BACE-1 inhibitors (Alzheimer's disease); BACE-1 inhibitors (Alzheimer's disease), Merck & Co; BACE-1 inhibitors (Alzheimer's disease), Schering-Plough; Beta-secretase inhibitors (Alzheimer's disease), Schering-Plough
Drug Type
Small molecular drug
Indication Alzheimer disease [ICD9: 331; ICD10:G30] Preclinical [548013]
Company
Schering-Plough Corp
Structure
Download
2D MOL

3D MOL

Formula
C18H18N4OS
Canonical SMILES
N1C(CC(=O)N(C1=N)C)(c1scc(c1)c1cc(cnc1)C#CC)C
PubChem Compound ID
Target and Pathway
Target(s) Beta-secretase Target Info Inhibitor [551869]
References
Ref 548013Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021196)
Ref 551869ACS Meeting News: Using chemistry tools to refine an Alzheimer's drug candidate. C&EN. April 5, 2010. Volume 88, Number 14 p.14.

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