Drug Information
Drug General Information | |||||
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Drug ID |
D0DK8V
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Former ID |
DAP000323
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Drug Name |
Cetirizine
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Synonyms |
Cetiderm; Cetirizin; Cetirizina; Cetirizinum; Cetryn; Setir; Virlix; Ziptek; Zirtek; Zyrlex; Cetirizina [Spanish]; Cetirizinum [Latin]; Cetrizine Hcl; Hitrizin Film Tablet; Cetiderm (TN); Cetirizine (INN); Cetirizine [INN:BAN]; P-071; Reactine (TN); Zyrtec (TN); [(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethyl)oxy]acetic acid; (2-(4-((4-Chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)acetic acid; (2-{4-[(4-Chloro-phenyl)-phenyl-methyl]-piperazin-1-yl}-ethoxy)-acetic acid; (2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid; 2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid; 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid
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Drug Type |
Small molecular drug
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Therapeutic Class |
Antiallergic Agents
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Company |
Pfizer Pharmaceuticals
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Structure |
Download2D MOL |
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Formula |
C21H25ClN2O3
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InChI |
InChI=1S/C21H25ClN2O3/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26/h1-9,21H,10-16H2,(H,25,26)
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InChIKey |
ZKLPARSLTMPFCP-UHFFFAOYSA-N
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CAS Number |
CAS 83881-51-0
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PubChem Compound ID | |||||
PubChem Substance ID |
9980, 853774, 5658851, 7978899, 8151737, 11466531, 11467651, 11486082, 11501857, 14756386, 29221835, 46508368, 47359454, 47583265, 47953980, 48179259, 48403972, 48415747, 49698526, 49846704, 49861380, 50112918, 50112919, 50112920, 50276923, 51091966, 57321395, 57581408, 81041207, 85209379, 85788875, 90341832, 92290962, 92721266, 93624540, 103266652, 104170194, 104301286, 108136263, 117611598, 117843325, 121362416, 124526347, 125324646, 125339821, 125544920, 125822846, 126525325, 126582564, 126619301
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ChEBI ID |
ChEBI:3561
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SuperDrug ATC ID |
R06AE07
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SuperDrug CAS ID |
cas=083881510
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Target and Pathway | |||||
Target(s) | Histamine H1 receptor | Target Info | Antagonist | [535660], [537488] | |
PANTHER Pathway | Histamine H1 receptor mediated signaling pathway | ||||
References | |||||
Ref 534869 | Comparative tolerability of second generation antihistamines. Drug Saf. 1999 May;20(5):385-401. | ||||
Ref 538734 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1222). | ||||
Ref 535660 | Knockouts model the 100 best-selling drugs--will they model the next 100? Nat Rev Drug Discov. 2003 Jan;2(1):38-51. | ||||
Ref 537488 | Design, synthesis and histamine H1-receptor antagonistic activity of some novel 4-amino-2-(substituted)-5-(substituted) aryl-6-[(substituted aryl) amino] pyrimidines. Arzneimittelforschung. 2009;59(5):243-7. |
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