Drug Information
Drug General Information | |||||
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Drug ID |
D0CS2C
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Former ID |
DCL000487
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Drug Name |
AZD9056
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Drug Type |
Small molecular drug
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Company |
AstraZeneca
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Structure |
Download2D MOL |
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Formula |
C24H35ClN2O2
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InChI |
InChI=1S/C24H35ClN2O2/c25-22-5-4-17(3-1-6-26-7-2-8-28)12-21(22)23(29)27-16-24-13-18-9-19(14-24)11-20(10-18)15-24/h4-5,12,18-20,26,28H,1-3,6-11,13-16H2,(H,27,29)
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InChIKey |
HSQAARMBHJCUOK-UHFFFAOYSA-N
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CAS Number |
CAS 847254-30-2
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | P2X purinoceptor 7 | Target Info | Antagonist | [550288] | |
Reactome | The NLRP3 inflammasome | ||||
References | |||||
Ref 522096 | ClinicalTrials.gov (NCT00520572) A 6-month Randomised, Double-blind, Open Arm Comparator, Phase IIb, With AZD9056, in Patients With Rheumatoid Arthritis (RA). U.S. National Institutes of Health. | ||||
Ref 542771 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7826). |
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