Drug General Information
Drug ID
D0CJ0P
Former ID
DNC000652
Drug Name
Flavone-8-acetic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535352]
Structure
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2D MOL

3D MOL

Formula
C17H12O4
Canonical SMILES
C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=CC=C3)CC(=O)O
InChI
1S/C17H12O4/c18-14-10-15(11-5-2-1-3-6-11)21-17-12(9-16(19)20)7-4-8-13(14)17/h1-8,10H,9H2,(H,19,20)
InChIKey
TZZNWMJZDWYJAZ-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Von Willebrand factor Target Info Inhibitor [535352]
KEGG Pathway PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Complement and coagulation cascades
Platelet activation
PANTHER Pathway Blood coagulation
Inflammation mediated by chemokine and cytokine signaling pathway
Reactome Platelet degranulation
Intrinsic Pathway of Fibrin Clot Formation
Integrin cell surface interactions
Integrin alphaIIb beta3 signaling
GRB2:SOS provides linkage to MAPK signaling for Integrins
p130Cas linkage to MAPK signaling for integrins
GP1b-IX-V activation signalling
MAP2K and MAPK activation
Platelet Adhesion to exposed collagen
WikiPathways Complement and Coagulation Cascades
Focal Adhesion
Blood Clotting Cascade
Platelet Adhesion to exposed collagen
Integrin alphaIIb beta3 signaling
GP1b-IX-V activation signalling
Formation of Fibrin Clot (Clotting Cascade)
References
Ref 535352Novel approaches to the treatment of thrombosis. Trends Pharmacol Sci. 2002 Jan;23(1):25-32.
Ref 535352Novel approaches to the treatment of thrombosis. Trends Pharmacol Sci. 2002 Jan;23(1):25-32.

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