TTD | Drug: D0C9JL

Drug General Information
Drug ID	D0C9JL
Former ID	DIB015243
Drug Name	Y-23684
Synonyms	2-(4-Chlorophenyl)-2,3,5,6-tetrahydro[1]benzothiepino[5,4-c]pyridazin-3-one 7-oxide
Drug Type	Small molecular drug
Indication	Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42]		Discontinued in Phase 3	[544030]
Structure		Download 2D MOL 3D MOL
Formula	C18H13ClN2O2S
Canonical SMILES	C1CS(=O)C2=CC=CC=C2C3=NN(C(=O)C=C31)C4=CC=C(C=C4)Cl
InChI	1S/C18H13ClN2O2S/c19-13-5-7-14(8-6-13)21-17(22)11-12-9-10-24(23)16-4-2-1-3-15(16)18(12)20-21/h1-8,11H,9-10H2
InChIKey	WHMCSFWQVGJBGM-UHFFFAOYSA-N
PubChem Compound ID	195253
PubChem Substance ID	10262044, 14852306, 17395836, 33515702, 75418786, 113460351, 135171901, 144240349, 162945430, 223444582, 224906241, 232927849
Target and Pathway
Target(s)	GABA A receptor	Target Info	Modulator	[533803]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
Reactome	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 544030	The pharmacological properties of Y-23684, a benzodiazepine receptor partial agonist.. Br J Pharmacol. 1994 April; 111(4): 1170-1178.
Ref 533803	The pharmacological properties of Y-23684, a benzodiazepine receptor partial agonist. Br J Pharmacol. 1994 Apr;111(4):1170-8.

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Drug Information