Drug Information

Drug General Information
Drug ID
D0C2QF
Former ID
DPR000068
Drug Name
LY-25582
Drug Type
Small molecular drug
Indication Obesity [ICD9: 278; ICD10:E66] Preclinical [536122]
Company
Eli Lilly
Structure
Download
2D MOL

3D MOL
Formula
C22H35NO2
Canonical SMILES
CC1CN(CCC1(C)C2=CC(=CC=C2)O)CCC(C3CCCCC3)O
InChI
1S/C22H35NO2/c1-17-16-23(13-11-21(25)18-7-4-3-5-8-18)14-12-22(17,2)19-9-6-10-20(24)15-19/h6,9-10,15,17-18,21,24-25H,3-5,7-8,11-14,16H2,1-2H3/t17-,21-,22+/m0/s1
InChIKey
LVVHEFJXPXAUDD-BULFRSBZSA-N
PubChem Compound ID
9906198
PubChem Substance ID
14875966, 24187638, 45977863, 77090391, 103234501, 103976648, 128548843, 134345007, 140075420, 228824878, 252450989
Target and Pathway
Target(s) Mu-type opioid receptor Target Info Antagonist [536122]
KEGG Pathway Neuroactive ligand-receptor interaction
Estrogen signaling pathway
Morphine addiction
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Enkephalin release
Pathway Interaction Database IL4-mediated signaling events
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways TCR Signaling Pathway
GPCRs, Class A Rhodopsin-like
Peptide GPCRs
Opioid Signalling
GPCR ligand binding
GPCR downstream signaling
References
Ref 536122Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.
Ref 536122Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.

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