Drug Information

Drug General Information
Drug ID
D0C2II
Former ID
DIB007321
Drug Name
Methazolamide
Synonyms
Methazolamide (oral, sustained release)
Drug Type
Small molecular drug
Indication Glaucoma [ICD9: 365; ICD10:H40-H42] Approved [525219], [541909]
Company
Effcon Laboratories Inc
Structure
Download
2D MOL

3D MOL
Formula
C5H8N4O3S2
InChI
InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)
InChIKey
FLOSMHQXBMRNHR-UHFFFAOYSA-N
PubChem Compound ID
4100
PubChem Substance ID
9966, 855821, 3258317, 5065191, 7847721, 8149959, 8152572, 10321916, 10526959, 11112413, 11335757, 11360996, 11364509, 11367071, 11369633, 11373107, 11373878, 11377795, 11461968, 11466830, 11467950, 11485122, 11486320, 11489359, 11491729, 11492005, 11495429, 14847334, 15220808, 24896908, 26612448, 26679700, 26747005, 26747006, 29223209, 42681260, 46506393, 46511451, 47349546, 47349547, 47662261, 47943968, 47959722, 48019113, 48019114, 48243575, 48416240, 49699038, 49859977, 50100905
Target and Pathway
Target(s) Carbonic anhydrase I Target Info Modulator [543654]
KEGG Pathway Nitrogen metabolism
Pathway Interaction Database C-MYB transcription factor network
PathWhiz Pathway Gastric Acid Production
Reactome Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Reversible hydration of carbon dioxide
WikiPathways Reversible Hydration of Carbon Dioxide
Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
References
Ref 525219ClinicalTrials.gov (NCT02463357) Three New Ideas to Protect Special Forces From the Stress of High Altitude.
Ref 541909(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6828).
Ref 543654(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2597).

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