Drug Information
Drug General Information | |||||
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Drug ID |
D0C1SI
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Former ID |
DNC003847
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Drug Name |
MK-386
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Drug Type |
Small molecular drug
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Indication | Acne vulgaris [ICD9: 706.1; ICD10:L70.0] | Discontinued in Phase 2 | [546066] | ||
Structure |
Download2D MOL |
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Formula |
C28H49NO
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Canonical SMILES |
CC1CC2C(CCC(=O)N2C)(C3C1C4CCC(C4(CC3)C)C(C)CCCC(C)C)C
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InChI |
1S/C28H49NO/c1-18(2)9-8-10-19(3)21-11-12-22-26-20(4)17-24-28(6,16-14-25(30)29(24)7)23(26)13-15-27(21,22)5/h18-24,26H,8-17H2,1-7H3
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InChIKey |
XUTZDXHKQDPUMA-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | Target Info | Inhibitor | [525719] | |
KEGG Pathway | Steroid hormone biosynthesis | ||||
NetPath Pathway | IL2 Signaling Pathway | ||||
PathWhiz Pathway | Androgen and Estrogen Metabolism | ||||
Reactome | Androgen biosynthesis | ||||
References |
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