Drug Information

Drug General Information
Drug ID
D0C1EQ
Former ID
DNC009963
Drug Name
2-(2-(biphenyl-4-yl)ethylthio)acetic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530333]
Structure
Download
2D MOL

3D MOL
Formula
C16H16O2S
Canonical SMILES
C1=CC=C(C=C1)C2=CC=C(C=C2)CCSCC(=O)O
InChI
1S/C16H16O2S/c17-16(18)12-19-11-10-13-6-8-15(9-7-13)14-4-2-1-3-5-14/h1-9H,10-12H2,(H,17,18)
InChIKey
VNCUHIXOCDBZGU-UHFFFAOYSA-N
PubChem Compound ID
20348772
Target and Pathway
Target(s) MMP-12 Target Info Inhibitor [530333]
NetPath Pathway IL1 Signaling Pathway
IL5 Signaling Pathway
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome Collagen degradation
Degradation of the extracellular matrix
WikiPathways TGF beta Signaling Pathway
Degradation of collagen
Matrix Metalloproteinases
References
Ref 530333Bioorg Med Chem Lett. 2009 Oct 1;19(19):5760-3. Epub 2009 Aug 6.The identification of beta-hydroxy carboxylic acids as selective MMP-12 inhibitors.
Ref 530333Bioorg Med Chem Lett. 2009 Oct 1;19(19):5760-3. Epub 2009 Aug 6.The identification of beta-hydroxy carboxylic acids as selective MMP-12 inhibitors.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.