Drug General Information
Drug ID	D0BN7W
Former ID	DIB002031
Drug Name	Roclatan
Synonyms	PG324
Indication	Glaucoma [ICD9: 365; ICD10:H40-H42]		Phase 3	[525325]
Company	Aerie pharmaceuticals
Structure		Download 2D MOL
Target and Pathway
Target(s)	Sodium-dependent noradrenaline transporter	Target Info	Modulator	[1572591]
	Rho associated protein kinase	Target Info	Modulator	[1572591]
PANTHER Pathway	Adrenaline and noradrenaline biosynthesis
Reactome	Na+/Cl- dependent neurotransmitter transporters
WikiPathways	Monoamine Transport
	NRF2 pathway
	Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
References
Ref 525325	ClinicalTrials.gov (NCT02558400) Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension.
Ref 1572591	Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.

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