Drug Information

Drug General Information
Drug ID
D0BB7F
Former ID
DNC008453
Drug Name
4-butyl-N-(isoquinolin-5-yl)benzamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529389]
Structure
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2D MOL

3D MOL
Formula
C20H20N2O
Canonical SMILES
CCCCC1=CC=C(C=C1)C(=O)NC2=CC=CC3=C2C=CN=C3
InChI
1S/C20H20N2O/c1-2-3-5-15-8-10-16(11-9-15)20(23)22-19-7-4-6-17-14-21-13-12-18(17)19/h4,6-14H,2-3,5H2,1H3,(H,22,23)
InChIKey
FBFHYVLRXNNMSE-UHFFFAOYSA-N
PubChem Compound ID
44450355
Target and Pathway
Target(s) Vanilloid receptor 1 Target Info Inhibitor [529389]
KEGG Pathway Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
NetPath Pathway IL2 Signaling Pathway
Pathway Interaction Database Trk receptor signaling mediated by the MAPK pathway
Trk receptor signaling mediated by PI3K and PLC-gamma
Reactome TRP channels
References
Ref 529389Bioorg Med Chem Lett. 2008 Apr 15;18(8):2730-4. Epub 2008 Mar 5.N-pyridin-3-yl- and N-quinolin-3-yl-benzamides: modulators of human vanilloid receptor 1 (TRPV1).
Ref 529389Bioorg Med Chem Lett. 2008 Apr 15;18(8):2730-4. Epub 2008 Mar 5.N-pyridin-3-yl- and N-quinolin-3-yl-benzamides: modulators of human vanilloid receptor 1 (TRPV1).

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