Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0B5BG
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| Former ID |
DNC003646
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| Drug Name |
6-Benzyloxy-9H-purin-2-ylamine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C12H11N5O
|
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| Canonical SMILES |
C1=CC=C(C=C1)COC2=NC(=NC3=C2NC=N3)N
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| InChI |
1S/C12H11N5O/c13-12-16-10-9(14-7-15-10)11(17-12)18-6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H3,13,14,15,16,17)
|
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| InChIKey |
KRWMERLEINMZFT-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Methylated-DNA--protein-cysteine methyltransferase | Target Info | Inhibitor | [1] | |
| WikiPathways | DNA Damage Reversal | ||||
| References | |||||
| REF 1 | J Med Chem. 1998 Feb 12;41(4):503-8.Inhibition of human O6-alkylguanine-DNA alkyltransferase and potentiation of the cytotoxicity of chloroethylnitrosourea by 4(6)-(benzyloxy)-2,6(4)-diamino-5-(nitroor nitroso)pyrimidine derivatives and analogues. | ||||
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