Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0B0YD
|
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| Former ID |
DNC000987
|
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| Drug Name |
N-alpha-methyl histamine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C6H11N3
|
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| InChI |
InChI=1S/C6H11N3/c1-7-3-2-6-4-8-5-9-6/h4-5,7H,2-3H2,1H3,(H,8,9)
|
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| InChIKey |
PHSPJQZRQAJPPF-UHFFFAOYSA-N
|
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| CAS Number |
CAS 673-50-7
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
5065181, 11113574, 15297184, 24439270, 26751779, 29215030, 47359864, 48105153, 49846344, 49846717, 49979813, 50831849, 57320585, 85177326, 85209211, 103100396, 103173300, 104296219, 117521462, 126406961, 126562153, 126581284, 126738242, 128917699, 131475502, 132630686, 134351295, 134978108, 135650394, 135650398, 136351124, 141951908, 142358121, 152045421, 164816575, 179293845, 184585654, 198969008, 226490982, 228232104, 243812317, 249209407, 249945440
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| Target and Pathway | |||||
| Target(s) | Histamine H4 receptor | Target Info | Agonist | [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Reactome | Histamine receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | GPCR ligand binding | ||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1239). | ||||
| REF 2 | Histamine induces cytoskeletal changes in human eosinophils via the H(4) receptor. Br J Pharmacol. 2003 Nov;140(6):1117-27. Epub 2003 Oct 6. | ||||
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