Drug General Information
Drug ID	D0B0PP
Former ID	DNC010219
Drug Name	3,3-diphenylpropan-1-amine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530331]
Structure		Download 2D MOL 3D MOL
Formula	C15H17N
Canonical SMILES	C1=CC=C(C=C1)C(CCN)C2=CC=CC=C2
InChI	1S/C15H17N/c16-12-11-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10,15H,11-12,16H2
InChIKey	KISZTEOELCMZPY-UHFFFAOYSA-N
PubChem Compound ID	79698
Target and Pathway
Target(s)	Histamine H1 receptor	Target Info	Inhibitor	[530331]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Inflammatory mediator regulation of TRP channels
PANTHER Pathway	Histamine H1 receptor mediated signaling pathway
Reactome	Histamine receptors
	G alpha (q) signalling events
WikiPathways	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	IL-4 Signaling Pathway
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 530331	Bioorg Med Chem. 2009 Sep 15;17(18):6496-504. Epub 2009 Aug 13.Synthesis, structure-affinity relationships, and modeling of AMDA analogs at 5-HT2A and H1 receptors: structural factors contributing to selectivity.
Ref 530331	Bioorg Med Chem. 2009 Sep 15;17(18):6496-504. Epub 2009 Aug 13.Synthesis, structure-affinity relationships, and modeling of AMDA analogs at 5-HT2A and H1 receptors: structural factors contributing to selectivity.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.