Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0AO5H
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| Former ID |
DAP000927
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| Drug Name |
Trimethoprim
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| Synonyms |
Abaprim; Alprim; Anitrim; Antrima; Antrimox; Bacdan; Bacidal; Bacide; Bacin; Bacta; Bacterial; Bacticel; Bactin; Bactoprim; Bactramin; Bencole; Bethaprim; Biosulten; Briscotrim; Chemotrin; Cidal; Colizole; Conprim; Cotrimel; Deprim; Duocide; Esbesul; Espectrin; Euctrim; Exbesul; Fermagex; Fortrim; Futin; Idotrim; Ikaprim; Instalac; Kombinax; Lagatrim; Lastrim; Methoprim; Metoprim; Monoprim; Monotrim; Monotrimin; Novotrimel; Omstat; Oraprim; Pancidim; Polytrim; Priloprim; Primosept; Primsol; Proloprim; Protrin; Purbal; Resprim; Roubac; Roubal; Salvatrim; Setprin; Sinotrim; Stopan; Streptoplus; Sugaprim; Sulfamar; Sulfamethoprim; Sulfoxaprim; Sulmeprim; Sulthrim; Sultrex; Syraprim; Tiempe; Toprim; Trimanyl; Trimethioprim; Trimethoprime; Trimethoprimum; Trimethopriom; Trimetoprim; Trimetoprima; Trimexazole; Trimexol; Trimezol; Trimogal; Trimono; Trimopan; Trimpex; Triprim; Trisul; Trisulcom; Trisulfam; Trisural; Uretrim; Urobactrim; Utetrin; Velaten; Wellcoprim; Wellcoprin; Xeroprim; Zamboprim; Bacterial [Antibiotic]; Colizole DS; Component of Bactrim; Component of Septra; Lagatrim Forte; ResprimForte; Septrin DS; Septrin Forte; Septrin S; Trimetoprim [DCIT]; Trimetoprim [Polish]; BW 5672; KUC103659N; NIH 204; T 7883; Trimpex 200; WR 5949; Alcorim-F; Apo-Sulfatrim; BW 56-72; Co-Trimoxizole; Monotrim (TN); NIH 204 (VAN); Proloprim (TN); Smz-Tmp; Sulfamethoxazole & Trimethoprim; TCMDC-125538; Tmp-Ratiopharm; Trimeth/Sulfa; Trimethopim(TMP); Trimethoprim & VRC3375; Trimethoprime [INN-French]; Trimethoprimum [INN-Latin]; Trimetoprima [INN-Spanish]; Trimez-IFSA; Trimpex (TN); Triprim (TN); U-Prin; Uro-D S; BW-56-72; KSC-4-158; TMP/SMX (MIXTURE)); AZT + TMP/SMX (mixture) combination; Trimethoprim (JAN/USP/INN); Trimethoprim [USAN:BAN:INN:JAN]; TMP
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| Drug Type |
Small molecular drug
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| Indication | Urinary tract infections [ICD9: 599; ICD10:N39.0] | Approved | [536854] | ||
| Therapeutic Class |
Antiinfective Agents
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| Company |
GlaxoSmithKline
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| Structure |
|
Download2D MOL |
|||
| Formula |
C14H18N4O3
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| Canonical SMILES |
COC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N
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| InChI |
1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18)
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| InChIKey |
IEDVJHCEMCRBQM-UHFFFAOYSA-N
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| CAS Number |
CAS 738-70-5
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| PubChem Compound ID | |||||
| PubChem Substance ID |
5066, 406777, 604810, 837167, 857743, 3146445, 4752045, 7847213, 7890832, 7980835, 8027414, 8149571, 8153433, 10321479, 10534335, 11111923, 11111924, 11113621, 11335764, 11361003, 11363061, 11365623, 11368185, 11371565, 11374002, 11376347, 11461975, 11466236, 11467356, 11484610, 11485852, 11488753, 11490459, 11492187, 11493981, 14824824, 17389524, 17405825, 22391545, 24278201, 24870616, 24889615, 25623645, 26611964, 26680042, 26697109, 26704777, 26747124, 26747125, 26751820
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| ChEBI ID |
ChEBI:45924
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| SuperDrug ATC ID |
J01EA01
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| SuperDrug CAS ID |
cas=000738705
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| Drug Resistance Mutation (DRM) | |||||
| DRM | DRM Info | ||||
| Target and Pathway | |||||
| Target(s) | DHFR | Target Info | Modulator | [556264] | |
| PANTHER Pathway | Tetrahydrofolate biosynthesis | ||||
| Formyltetrahydroformate biosynthesis | |||||
| Pathway Interaction Database | E2F transcription factor network | ||||
| PathWhiz Pathway | Folate Metabolism | ||||
| Pterine Biosynthesis | |||||
| References | |||||
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