Drug Information

Drug General Information
Drug ID
D0AD4H
Former ID
DCL000747
Drug Name
Cethrin
Drug Type
Small molecular drug
Indication Spinal cord injury [ICD10:S14, S24, S34] Phase 1/2 [536648]
Company
Alseres Pharmaceuticals Purchased rights for Cethrin from BioAxone Therapeutic
Structure
Download
2D MOL

3D MOL
Formula
C23H32Cl3N3O
Canonical SMILES
CCN(CC)CCCC(C)NC1=C2C=C3C=C(C=CC3=NC2=CC(=C1)Cl)OC.Cl.C<br />l
InChI
1S/C23H30ClN3O.2ClH/c1-5-27(6-2)11-7-8-16(3)25-22-14-18(24)15-23-20(22)13-17-12-19(28-4)9-10-21(17)26-23;;/h9-10,12-16,25H,5-8,11H2,1-4H3;2*1H
InChIKey
QKAZHUGLNKCCGY-UHFFFAOYSA-N
PubChem Compound ID
16760629
PubChem Substance ID
26759430, 57309657, 134339238, 134340210, 163687423
SuperDrug ATC ID
P01AX05
SuperDrug CAS ID
cas=000083896
Target and Pathway
Target(s) Rho associated protein kinase Target Info Modulator [531381]
References
Ref 536648Emerging drugs for spinal cord injury. Expert Opin Emerg Drugs. 2008 Mar;13(1):63-80.
Ref 531381A phase I/IIa clinical trial of a recombinant Rho protein antagonist in acute spinal cord injury. J Neurotrauma. 2011 May;28(5):787-96.

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