Drug Information

Drug General Information
Drug ID
D0A1KR
Former ID
DIB014655
Drug Name
JTK-652
Synonyms
HCV NS5B polymerase inhibitors (JTK-109 derivatives), Japan Tobacco; JTK-109 derivatives (HCV), Japan Tobacco
Indication HCV infection [ICD9: 070.4, 070.5, 070.70; ICD10:B17.1, B18.2] Discontinued in Phase 1 [548657]
Company
Japan Tobacco Inc
Structure
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2D MOL

3D MOL
Canonical SMILES
C(=O)(O)c1cc2c(c(C3CCCCC3)c3n2CCOc2c3ccc(c2)OCc2ccccc2)<br />cc1
Target and Pathway
Target(s) Hepatitis C virus NS5B polymerase Target Info Inhibitor [531105]
References
Ref 548657Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027431)
Ref 531105Safety and antiviral activity of JTK-652: a novel HCV infection inhibitor. Antivir Ther. 2010;15(5):765-73.

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