Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0A0MU
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| Former ID |
DIB006768
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| Drug Name |
FOZIVUDINE TIDOXIL
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| Synonyms |
HDP-990002; BM-21.1290; Fozivudine tidoxil < Prop INN >; 3'-Azido-3'-deoxy-5'-O-[2-decyloxy-3-(dodecylthio)propoxy-hydroxyphosphoryl]thymidine
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| Drug Type |
Small molecular drug
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| Indication | Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] | Discontinued in Phase 2 | [546321] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C35H64N5O8PS
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| Canonical SMILES |
CCCCCCCCCCCCSC[C@@H](COP(=O)(O)OC[C@H]1O[C@H](C[C@H]1N=<br />[N+]=[N-])N2C=C(C)C(=O)NC2=O)OCCCCCCCCCC
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| InChI |
1S/C35H64N5O8PS/c1-4-6-8-10-12-14-15-17-19-21-23-50-28-30(45-22-20-18-16-13-11-9-7-5-2)26-46-49(43,44)47-27-32-31(38-39-36)24-33(48-32)40-25-29(3)34(41)37-35(40)42/h25,30-33H,4-24,26-28H2,1-3H3,(H,43,44)(H,37,41,42)/t30-,31-,32-,33-/m1/s1
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| InChIKey |
IBHARWXWOCPXCR-XEXPGFJZSA-N
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| CAS Number |
CAS 141790-23-0
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | HIV reverse transcriptase | Target Info | Inhibitor | [531419], [551871] | |
| References | |||||
| Ref 531419 | Fozivudine tidoxil as single-agent therapy decreases plasma and cell-associated viremia during acute feline immunodeficiency virus infection. J Vet Intern Med. 2011 May-Jun;25(3):413-8. | ||||
| Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | ||||
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