Drug General Information
Drug ID
D0A0GD
Former ID
DNC002973
Drug Name
3-Hydroxy-Myristic Acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL

3D MOL

Formula
C14H27O3-
Canonical SMILES
CCCCCCCCCCCC(CC(=O)[O-])O
InChI
1S/C14H28O3/c1-2-3-4-5-6-7-8-9-10-11-13(15)12-14(16)17/h13,15H,2-12H2,1H3,(H,16,17)/p-1
InChIKey
ATRNZOYKSNPPBF-UHFFFAOYSA-M
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Lymphocyte antigen 96 Target Info Inhibitor [551393]
Toll-like receptor 4 Target Info Inhibitor [551393]
KEGG Pathway NF-kappa B signaling pathway
Toll-like receptor signaling pathway
Pathogenic Escherichia coli infection
Pertussis
Toxoplasmosishsa04064:NF-kappa B signaling pathway
HIF-1 signaling pathway
Phagosome
PI3K-Akt signaling pathway
Salmonella infection
Legionellosis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Malaria
Toxoplasmosis
Amoebiasis
Tuberculosis
Hepatitis B
Measles
Influenza A
Proteoglycans in cancer
Inflammatory bowel disease (IBD)
Rheumatoid arthritis
NetPath Pathway TGF_beta_Receptor Signaling Pathway
IL6 Signaling PathwayNetPath_17:IL5 Signaling Pathway
IL2 Signaling Pathway
IL4 Signaling Pathway
PANTHER Pathway Toll receptor signaling pathwayP00054:Toll receptor signaling pathway
Pathway Interaction Database Endogenous TLR signalingtoll_endogenous_pathway:Endogenous TLR signaling
Reactome Ligand-dependent caspase activation
Toll Like Receptor 4 (TLR4) Cascade
MyD88:Mal cascade initiated on plasma membrane
MyD88-independent TLR3/TLR4 cascade
TRIF-mediated programmed cell death
MyD88 deficiency (TLR2/4)
IRAK4 deficiency (TLR2/4)
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
IKK complex recruitment mediated by RIP1
TRAF6 mediated induction of TAK1 complexR-HSA-140534:Ligand-dependent caspase activation
TRAF6 mediated induction of TAK1 complex
WikiPathways Toll-like receptor signaling pathway
Toll-Like Receptors Cascades
MyD88:Mal cascade initiated on plasma membrane
MyD88-independent cascade
Pathogenic Escherichia coli infection
Regulation of toll-like receptor signaling pathwayWP75:Toll-like receptor signaling pathway
Primary Focal Segmental Glomerulosclerosis FSGS
Spinal Cord Injury
Corticotropin-releasing hormone
Regulation of toll-like receptor signaling pathway
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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