Drug Information
Drug General Information | |||||
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Drug ID |
D09ZQN
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Former ID |
DAP001015
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Drug Name |
Dienestrol
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Synonyms |
Agaldog; Cycladiene; Dehydrostilbestrol; Dehydrostilboestrol; Dienesterol; Dienestrolo; Dienestrolum; Dienoestrol; Dienol; Dinestrol; Dinovex; Estragard; Estraguard; Estrodienol; Estroral; Follidiene; Follormon; Gynefollin; Hormofemin; Isodienestrol; Oestrasid; Oestrodiene; Oestrodienol; Oestroral; Oestrovis; Restrol; Retalon; Sexadien; Synestrol; Teserene; Willnestrol; Dienestrolo [DCIT]; Dienoestrol [Nonsteroidal oestrogens]; Dienoestrol bp; Alpha-Dienestrol; DV (TN); Dienestrolum [INN-Latin]; Para-Dien; Restrol, Dienestrol; Dienestrol (E,E); Dienestrol (USP/INN); Dienestrol, (E,E)-Isomer; P,p'-(Diethylideneethylene)diphenol; Para,para'-(Diethylideneethylene)diphenol; Di(p-oxyphenyl)-2,4-hexadiene; Di(para-oxyphenyl)-2,4-hexadiene; Phenol, 4,4'-(1,2-diethylidene-1,2-ethanediyl)bis-, (E,E-(9CI); (E,E)-Dienestrol; 3,4-Bis(4-hydroxyphenyl)-2,4-hexadiene; 3,4-Bis(p-hydroxyphenyl)-2,4-hexadiene; 3,4-Bis(para-hydroxyphenyl)-2,4-hexadiene; 4,4'-(1,2-Diethylidene-1,2-ethanediyl)bisphenol; 4,4'-(2E,4E)-hexa-2,4-diene-3,4-diyldiphenol; 4,4'-(Diethylideneethylene)diphenol; 4,4'-Dihydroxy-gamma,delta-diphenyl-beta,delta-hexadiene; 4,4'-Hydroxy-gamma,delta-diphenyl-beta,delta-hexadiene; 4,4'-hexa-2,4-diene-3,4-diyldiphenol; 4-[(2E,4E)-4-(4-hydroxyphenyl)hexa-2,4-dien-3-yl]phenol
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Drug Type |
Small molecular drug
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Therapeutic Class |
Estrogens
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Structure |
Download2D MOL |
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Formula |
C18H18O2
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InChI |
InChI=1S/C18H18O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h3-12,19-20H,1-2H3/b17-3+,18-4+
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InChIKey |
NFDFQCUYFHCNBW-SCGPFSFSSA-N
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CAS Number |
CAS 84-17-3
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PubChem Compound ID | |||||
PubChem Substance ID |
10290, 855694, 866306, 7847962, 8149299, 9276660, 10321153, 10536837, 15491054, 24869916, 24893737, 26611700, 26679878, 26746961, 26746962, 46504661, 47213198, 47365224, 47589030, 47736513, 48035154, 48035155, 48110473, 48110474, 48421888, 49698645, 50005377, 50123454, 50123455, 50950224, 53786970, 56352870, 56422141, 57408484, 57650731, 85148346, 85789335, 87567123, 89850272, 92124048, 92125902, 92307444, 92712307, 99301859, 103134881, 103272138, 103913634, 104253404, 109839953, 117617823
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ChEBI ID |
ChEBI:4518
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SuperDrug ATC ID |
G03CB01; G03CC02
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SuperDrug CAS ID |
cas=000084173
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Target and Pathway | |||||
Target(s) | Estrogen receptor | Target Info | Agonist | [536915] | |
Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
Signaling events mediated by HDAC Class II | |||||
Plasma membrane estrogen receptor signaling | |||||
LKB1 signaling events | |||||
Regulation of Telomerase | |||||
ATF-2 transcription factor network | |||||
AP-1 transcription factor network | |||||
FOXM1 transcription factor network | |||||
Validated nuclear estrogen receptor alpha network | |||||
Signaling mediated by p38-alpha and p38-beta | |||||
FOXA1 transcription factor network | |||||
References | |||||
Ref 538391 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 006110. | ||||
Ref 542169 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7160). | ||||
Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
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