Drug Information

Drug General Information
Drug ID
D09ZFF
Former ID
DIB008199
Drug Name
HRC-101
Synonyms
Oxygain; HML-109
Indication Blood transfusion [ICD10:D50-D89] Terminated [547440]
Company
Ontario Inc
Target and Pathway
Target(s) Hemoglobin Target Info Modulator [528970]
KEGG Pathway African trypanosomiasis
Malaria
Reactome Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Scavenging of heme from plasma
WikiPathways Binding and Uptake of Ligands by Scavenger Receptors
Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
Factors involved in megakaryocyte development and platelet production
Folate Metabolism
Vitamin B12 Metabolism
Selenium Micronutrient Network
References
Ref 547440Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016356)
Ref 528970The novel hemoglobin-based oxygen carrier HRC 101 improves survival in murine sickle cell disease. Anesthesiology. 2007 Aug;107(2):281-7.

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