Drug Information
Drug General Information | |||||
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Drug ID |
D09YVU
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Former ID |
DNC008055
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Drug Name |
6-(3-aminopropyl)benzo[h]isoquinolin-1(2H)-one
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [529069] | ||
Structure |
Download2D MOL |
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Formula |
C16H16N2O
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Canonical SMILES |
C1=CC=C2C(=C1)C(=CC3=C2C(=O)NC=C3)CCCN
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InChI |
1S/C16H16N2O/c17-8-3-4-11-10-12-7-9-18-16(19)15(12)14-6-2-1-5-13(11)14/h1-2,5-7,9-10H,3-4,8,17H2,(H,18,19)
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InChIKey |
LBNJYZFAUIDIPA-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Serine/threonine-protein kinase Chk1 | Target Info | Inhibitor | [529069] | |
Pathway Interaction Database | Fanconi anemia pathway | ||||
p73 transcription factor network | |||||
ATR signaling pathway | |||||
Circadian rhythm pathway | |||||
p53 pathway | |||||
Reactome | Activation of ATR in response to replication stress | ||||
Processing of DNA double-strand break ends | |||||
Presynaptic phase of homologous DNA pairing and strand exchange | |||||
G2/M DNA damage checkpoint | |||||
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | |||||
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | |||||
References |
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