Drug General Information
Drug ID	D09XVQ
Former ID	DIB013339
Drug Name	PT-14
Synonyms	Erectide; PT-14 (transmucosal); PT-14 (transmucosal), Palatin/TheraTech
Indication	Erectile dysfunction [ICD9: 302.72, 607.84; ICD10:F52.2, N48.4]		Discontinued in Phase 2	[546757]
Company	Competitive Technologies Inc
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Melanocortin-4 receptor	Target Info	Agonist	[532570]
KEGG Pathway	Neuroactive ligand-receptor interaction
Pathway Interaction Database	Syndecan-3-mediated signaling events
Reactome	Peptide ligand-binding receptors
	G alpha (s) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 546757	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010143)
Ref 532570	The protective effects of the melanocortin receptor (MCR) agonist, melanotan-II (MTII), against binge-like ethanol drinking are facilitated by deletion of the MC3 receptor in mice. Neuropeptides. 2014 Feb;48(1):47-51.

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