Drug Information

Drug General Information
Drug ID
D09TVP
Former ID
DNC002588
Drug Name
Cacodylate Ion
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL

3D MOL
Formula
C2H7AsO2
Canonical SMILES
C[As](=O)(C)O
InChI
1S/C2H7AsO2/c1-3(2,4)5/h1-2H3,(H,4,5)
InChIKey
OGGXGZAMXPVRFZ-UHFFFAOYSA-N
PubChem Compound ID
2513
PubChem Substance ID
9516, 405276, 550112, 583643, 585540, 609263, 820929, 820955, 825024, 825305, 825315, 825331, 826127, 828436, 830633, 830847, 830886, 831497, 833146, 854580, 855157, 3152853, 5070549, 6436179, 8018167, 8022881, 8023029, 8027709, 8027881, 8028368, 8150092, 8151668, 10317216, 10317237, 10534914, 11335883, 11361122, 11364913, 11367475, 11370037, 11374068, 11378207, 11404479, 11405987, 11447883, 11447931, 11449379, 11462094, 11484895, 11488986
Target and Pathway
Target(s) Thyroid hormone receptor beta-1 Target Info Inhibitor [551393]
UDP-3-O-[3-hydroxymyristoyl] n-acetylglucosamine deacetylase Target Info Inhibitor [551393]
Nitric-oxide synthase, endothelial Target Info Inhibitor [551393]
Aspartate-semialdehydedehydrogenase Target Info Inhibitor [551393]
Thioredoxin Target Info Inhibitor [551393]
Calmodulin Target Info Inhibitor [551393]
BioCyc Pathway Citrulline-nitric oxide cycle
KEGG Pathway Neuroactive ligand-receptor interaction
Thyroid hormone signaling pathwaypae00540:Lipopolysaccharide biosynthesis
Metabolic pathwayshsa00330:Arginine and proline metabolism
Metabolic pathways
Calcium signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
Sphingolipid signaling pathway
PI3K-Akt signaling pathway
VEGF signaling pathway
Platelet activation
Estrogen signaling pathway
Oxytocin signaling pathwayhsa04014:Ras signaling pathway
Rap1 signaling pathway
cAMP signaling pathway
Phosphatidylinositol signaling system
Oocyte meiosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Circadian entrainment
Long-term potentiation
Neurotrophin signaling pathway
Dopaminergic synapse
Olfactory transduction
Phototransduction
Inflammatory mediator regulation of TRP channels
Insulin signaling pathway
GnRH signaling pathway
Melanogenesis
Oxytocin signaling pathway
Glucagon signaling pathway
Salivary secretion
Gastric acid secretion
Alzheimer's disease
Amphetamine addiction
Alcoholism
Pertussis
Tuberculosis
Glioma
NetPath Pathway Wnt Signaling PathwayNetPath_14:IL2 Signaling Pathway
RANKL Signaling PathwayNetPath_21:RANKL Signaling Pathway
TSH Signaling Pathway
PANTHER Pathway Angiogenesis
Endothelin signaling pathway
Interleukin signaling pathway
PI3 kinase pathway
VEGF signaling pathwayP00030:Hypoxia response via HIF activation
Oxidative stress responseP06959:CCKR signaling map ST
Pathway Interaction Database RXR and RAR heterodimerization with other nuclear receptorer_nongenomic_pathway:Plasma membrane estrogen receptor signaling
Validated transcriptional targets of AP1 family members Fra1 and Fra2
Angiopoietin receptor Tie2-mediated signaling
Thromboxane A2 receptor signaling
SHP2 signaling
VEGFR1 specific signals
Signaling events mediated by VEGFR1 and VEGFR2
PAR1-mediated thrombin signaling eventsp38_mkk3_6pathway:p38 MAPK signaling pathway
Signaling events mediated by PTP1B
TNF receptor signaling pathwaybcr_5pathway:BCR signaling pathway
p38 MAPK signaling pathway
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
Role of Calcineurin-dependent NFAT signaling in lymphocytes
IL2 signaling events mediated by PI3K
IFN-gamma pathway
Lissencephaly gene (LIS1) in neuronal migration and development
ErbB1 downstream signaling
Regulation of cytoplasmic and nuclear SMAD2/3 signaling
Calcium signaling in the CD4+ TCR pathway
Insulin-mediated glucose transport
N-cadherin signaling events
Cellular roles of Anthrax toxin
Regulation of Ras family activation
Downstream signaling in na&#xef
PathWhiz Pathway Purine MetabolismPW000564:Muscle/Heart Contraction
Reactome Nuclear Receptor transcription pathwayR-HSA-1222556:ROS production in response to bacteria
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
eNOS activation
Nitric oxide stimulates guanylate cyclase
VEGFR2 mediated vascular permeabilityR-HSA-2559580:Oxidative Stress Induced Senescence
Detoxification of Reactive Oxygen Species
TP53 Regulates Metabolic Genes
The NLRP3 inflammasomeR-HSA-111933:Calmodulin induced events
Platelet degranulation
Translocation of GLUT4 to the plasma membrane
DARPP-32 events
Inactivation, recovery and regulation of the phototransduction cascade
FCERI mediated Ca+2 mobilization
Ca2+ pathway
CREB phosphorylation through the activation of CaMKII
Ras activation uopn Ca2+ infux through NMDA receptor
Smooth Muscle Contraction
VEGFR2 mediated vascular permeability
VEGFR2 mediated cell proliferation
RHO GTPases activate IQGAPs
RAF/MAP kinase cascade
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
WikiPathways SIDS Susceptibility Pathways
Hematopoietic Stem Cell Differentiation
Nuclear ReceptorsWP554:ACE Inhibitor Pathway
EGF/EGFR Signaling Pathway
Myometrial Relaxation and Contraction Pathways
JAK/STAT
Corticotropin-releasing hormone
AGE/RAGE pathway
Endothelin Pathways
Leptin signaling pathway
Effects of Nitric Oxide
Metabolism of nitric oxide
AngiogenesisWP2884:NRF2 pathway
Nuclear Receptors Meta-Pathway
Detoxification of Reactive Oxygen Species
Human Complement System
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
TNF alpha Signaling Pathway
Metabolism of nucleotides
Selenium Micronutrient NetworkWP2777:Translocation of GLUT4 to the Plasma Membrane
Visual phototransduction
Fc epsilon receptor (FCERI) signaling
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Signaling by the B Cell Receptor (BCR)
Inositol phosphate metabolism
DAG and IP3 signaling
Opioid Signalling
Muscle contraction
Metabolism of carbohydrates
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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