Drug General Information
Drug ID	D09SCI
Former ID	DIB011195
Drug Name	SKF-104351
Drug Type	Small molecular drug
Indication	Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06]		Terminated	[544770]
Company	SmithKline Beecham plc
Structure		Download 2D MOL 3D MOL
Formula	C17H14FN3
Canonical SMILES	c1(nc2n(c1c1ccncc1)CCC2)c1ccc(cc1)F
CAS Number	CAS 111908-94-2
PubChem Compound ID	122656
Target and Pathway
Target(s)	Arachidonate 5-lipoxygenase	Target Info	Modulator	[550942]
BioCyc Pathway	Aspirin-triggered lipoxin biosynthesis
	Resolvin D biosynthesis
	Leukotriene biosynthesis
	Lipoxin biosynthesis
	Aspirin triggered resolvin D biosynthesis
	Aspirin triggered resolvin E biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Metabolic pathways
	Serotonergic synapse
	Ovarian steroidogenesis
	Toxoplasmosis
NetPath Pathway	IL4 Signaling Pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
WikiPathways	Vitamin D Receptor Pathway
	Arachidonic acid metabolism
	Eicosanoid Synthesis
	Selenium Micronutrient Network
References
Ref 544770	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000933)
Ref 550942	WO patent application no. 2006,1317,37, Method and composition for treating inflammatory disorders.

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