Drug Information
Drug General Information | |||||
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Drug ID |
D09QVV
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Former ID |
DAP000114
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Drug Name |
Vincristine
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Synonyms |
LCR; Leurocristine; Marqibo; Oncovine; Tecnocris; VCR; VIN; Vincasar; Vincristina; Vincristinum; Vincrstine; Vincrystine; Vinkristin; Indole alkaloid; Liposomal Vincristine; Onco TCS; Vincristina [DCIT]; Oncovin (TN); Tecnocris (TN); Vincristine (INN); Vincristine [INN:BAN]; Vincristinum [INN-Latin]; Lilly37231 (1:1 sulfate salt); Oncovin (1:1 sulfate salt); Vincasar (1:1 sulfate salt); Vincrex (1:1 sulfate salt); Vincaleukoblastine, 22-oxo-22-Oxovincaleukoblastine; Z-D-Val-Lys(Z)-OH; 22-Oxovincaleukoblastine
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Drug Type |
Small molecular drug
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Therapeutic Class |
Anticancer Agents
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Company |
Mayne Pharma Limited
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Structure |
Download2D MOL |
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Formula |
C46H56N4O10
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InChI |
InChI=1S/C46H56N4O10/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6/h9-13,15,20-21,26,28,37-39,47,55-56H,7-8,14,16-19,22-25H2,1-6H3/t28-,37+,38-,39-,42+,43-,44-,45+,46+/m1/s1
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InChIKey |
OGWKCGZFUXNPDA-XQKSVPLYSA-N
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CAS Number |
CAS 57-22-7
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PubChem Compound ID | |||||
PubChem Substance ID |
9413, 598397, 8153716, 11431056, 14717665, 14889382, 26757081, 29224994, 46507033, 48424284, 49854447, 53788615, 56312035, 56314177, 57323093, 74979043, 92309095, 96025362, 104029594, 104310773, 124892473, 124892475, 126687244, 127301091, 127301092, 127301093, 127301094, 127301095, 127301096, 127301097, 127301098, 127301099, 127301100, 127301101, 127301102, 127301103, 127301104, 127301105, 127301106, 127301107, 127301108, 127301109, 127301110, 127301111, 127301112, 127301113, 127301114, 127301115, 127301116, 127301117
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ChEBI ID |
ChEBI:28445
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SuperDrug ATC ID |
L01CA02
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SuperDrug CAS ID |
cas=000057227
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Target and Pathway | |||||
Target(s) | Tubulin beta | Target Info | Modulator | [556264] | |
PANTHER Pathway | Cytoskeletal regulation by Rho GTPase | ||||
Huntington disease | |||||
References | |||||
Ref 536556 | Vinflunine, a novel microtubule inhibitor, suppresses calmodulin interaction with the microtubule-associated protein STOP. Biochemistry. 2007 Dec 25;46(51):14899-906. Epub 2007 Dec 4. | ||||
Ref 541865 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6785). |
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