Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09QRO
|
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| Former ID |
DNC003737
|
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| Drug Name |
CGS-13080
|
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| Drug Type |
Small molecular drug
|
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| Indication | Asthma [ICD10:J45] | Terminated | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C13H16N2O2
|
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| Canonical SMILES |
C1=CC2=CN=CN2C(=C1)CCCCCC(=O)O
|
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| InChI |
1S/C13H16N2O2/c16-13(17)8-3-1-2-5-11-6-4-7-12-9-14-10-15(11)12/h4,6-7,9-10H,1-3,5,8H2,(H,16,17)
|
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| InChIKey |
LIFOFTJHFFTNRV-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Thromboxane-A synthase | Target Info | Inhibitor | [2] | |
| BioCyc Pathway | C20 prostanoid biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | ||||
| Metabolic pathways | |||||
| Platelet activation | |||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| WikiPathways | Prostaglandin Synthesis and Regulation | ||||
| Arachidonic acid metabolism | |||||
| Phase 1 - Functionalization of compounds | |||||
| Eicosanoid Synthesis | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000262) | ||||
| REF 2 | J Med Chem. 1985 Feb;28(2):164-70.Imidazo[1,5-a]pyridines: a new class of thromboxane A2 synthetase inhibitors. | ||||
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