TTD | Drug: D09ONV

Drug General Information
Drug ID	D09ONV
Former ID	DIB021182
Drug Name	VU0359516
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[541400]
Structure		Download 2D MOL 3D MOL
Formula	C16H13N3O3
InChI	InChI=1S/C16H13N3O3/c20-15(18-13-7-3-4-8-17-13)16-9-11(16)14(19-21)10-5-1-2-6-12(10)22-16/h1-8,11,21H,9H2,(H,17,18,20)/b19-14-
InChIKey	NAPZSTOOVHXHKA-RGEXLXHISA-N
PubChem Compound ID	73755197
Target and Pathway
Target(s)	Metabotropic glutamate receptor 4	Target Info	Modulator (allosteric modulator)	[530991]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Glutamatergic synapse
	Taste transduction
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
	Metabotropic glutamate receptor group III pathway
Reactome	G alpha (i) signalling events
Reactome	Class C/3 (Metabotropic glutamate/pheromone receptors)
WikiPathways	GPCRs, Class C Metabotropic glutamate, pheromone
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 541400	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6230).
Ref 530991	Re-exploration of the PHCCC Scaffold: Discovery of Improved Positive Allosteric Modulators of mGluR4. ACS Chem Neurosci. 2010 Jun 16;1(6):411-419.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information