Drug Information

Drug General Information
Drug ID
D09OHS
Former ID
DIB018613
Drug Name
4alpha-PDD
Synonyms
4alpha-phorbol 12,13-didecanoate; 4alpha-phorbol-didecanoate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539624]
Structure
Download
2D MOL
Formula
C40H64O8
InChI
InChI=1S/C40H64O8/c1-7-9-11-13-15-17-19-21-32(42)47-36-28(4)39(46)30(24-29(26-41)25-38(45)31(39)23-27(3)35(38)44)34-37(5,6)40(34,36)48-33(43)22-20-18-16-14-12-10-8-2/h23-24,28,30-31,34,36,41,45-46H,7-22,25-26H2,1-6H3/t28-,30+,31-,34-,36-,38+,39-,40-/m1/s1
InChIKey
DGOSGFYDFDYMCW-OEFRVDPMSA-N
PubChem Compound ID
452544
PubChem Substance ID
597734, 10300905, 26759351, 26759352, 53801079, 56351898, 57405350, 74968956, 103345887, 104098451, 104645160, 127731850, 135030605, 163687501, 163687502, 227765157, 241047842
Target and Pathway
Target(s) Transient receptor potential cation channel subfamily V member 4 Target Info Activator [526264]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 539624(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2500).
Ref 526264Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives. J Biol Chem. 2002 Apr 19;277(16):13569-77. Epub 2002 Feb 4.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.