Drug General Information
Drug ID	D09JAR
Former ID	DNC004964
Drug Name	BICARBONATE
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527389]
Structure		Download 2D MOL 3D MOL
Formula	CHO3-
Canonical SMILES	C(=O)(O)[O-]
InChI	1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1
InChIKey	BVKZGUZCCUSVTD-UHFFFAOYSA-M
PubChem Compound ID	769
Target and Pathway
Target(s)	Carbonic anhydrase IX	Target Info	Inhibitor	[527389]
KEGG Pathway	Nitrogen metabolism
Pathway Interaction Database	HIF-1-alpha transcription factor network
Reactome	Regulation of gene expression by Hypoxia-inducible Factor
	Reversible hydration of carbon dioxide
WikiPathways	Vitamin D Receptor Pathway
	Reversible Hydration of Carbon Dioxide
	Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
References
Ref 527389	Bioorg Med Chem Lett. 2005 Feb 1;15(3):567-71.Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate.
Ref 527389	Bioorg Med Chem Lett. 2005 Feb 1;15(3):567-71.Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate.

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