TTD | Drug: D09HFT

Drug General Information
Drug ID	D09HFT
Former ID	DNC007935
Drug Name	(E)-2-(4-fluorostyryl)-5-(phenylsulfonyl)pyridine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528690]
Structure		Download 2D MOL 3D MOL
Formula	C19H14FNO2S
Canonical SMILES	C1=CC=C(C=C1)S(=O)(=O)C2=CN=C(C=C2)C=CC3=CC=C(C=C3)F
InChI	1S/C19H14FNO2S/c20-16-9-6-15(7-10-16)8-11-17-12-13-19(14-21-17)24(22,23)18-4-2-1-3-5-18/h1-14H/b11-8+
InChIKey	ANNXZFGXMGNRDN-DHZHZOJOSA-N
PubChem Compound ID	44439376
Target and Pathway
Target(s)	5-hydroxytryptamine 2A receptor	Target Info	Inhibitor	[528690]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Serotonergic synapse
	Inflammatory mediator regulation of TRP channels
PANTHER Pathway	5HT2 type receptor mediated signaling pathway
Reactome	Serotonin receptors
Reactome	G alpha (q) signalling events
WikiPathways	Serotonin Receptor 2 and STAT3 Signaling
	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
	SIDS Susceptibility Pathways
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 528690	Bioorg Med Chem Lett. 2007 May 1;17(9):2643-8. Epub 2007 Feb 2.2,5-Disubstituted pyridines: the discovery of a novel series of 5-HT2A ligands.
Ref 528690	Bioorg Med Chem Lett. 2007 May 1;17(9):2643-8. Epub 2007 Feb 2.2,5-Disubstituted pyridines: the discovery of a novel series of 5-HT2A ligands.

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Drug Information