Drug Information
Drug General Information | |||||
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Drug ID |
D09FGQ
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Former ID |
DNC000588
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Drug Name |
E-64
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [535267] | ||
Structure |
Download2D MOL |
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Formula |
C15H27N5O5
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Canonical SMILES |
CC(C)CC(C(=O)NCCCCN=C(N)N)NC(=O)C1C(O1)C(=O)O
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InChI |
1S/C15H27N5O5/c1-8(2)7-9(20-13(22)10-11(25-10)14(23)24)12(21)18-5-3-4-6-19-15(16)17/h8-11H,3-7H2,1-2H3,(H,18,21)(H,20,22)(H,23,24)(H4,16,17,19)
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InChIKey |
LTLYEAJONXGNFG-UHFFFAOYSA-N
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CAS Number |
CAS 66701-25-5
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
ChEBI ID |
ChEBI:30270
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Target and Pathway | |||||
Target(s) | Plasmepsin 2 | Target Info | Inhibitor | [538124] | |
Cathepsin S | Target Info | Inhibitor | [535267] | ||
Cysteine proteinase | Target Info | Inhibitor | [538024] | ||
Plasmepsin 1 | Target Info | Inhibitor | [538124] | ||
NetPath Pathway | Leptin Signaling Pathway | ||||
IL2 Signaling Pathway | |||||
References | |||||
Ref 535267 | Baculoviral expression and characterization of rodent cathepsin S. Protein Expr Purif. 2001 Oct;23(1):45-54. | ||||
Ref 538024 | Characterization of a cysteine proteinase from Taenia crassiceps cysts. Mol Biochem Parasitol. 1997 Apr;85(2):243-53. | ||||
Ref 538124 | Antimalarial synergy of cysteine and aspartic protease inhibitors. Antimicrob Agents Chemother. 1998 Sep;42(9):2254-8. |
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