TTD | Drug: D09AZM

Drug General Information
Drug ID	D09AZM
Former ID	DIB021034
Drug Name	TEI-9063
Synonyms	TEI 9063
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539262]
Structure		Download 2D MOL
Formula	C23H38O4
InChI	InChI=1S/C23H38O4/c1-3-4-7-16(2)12-19(24)10-11-20-21-14-17(8-5-6-9-23(26)27)13-18(21)15-22(20)25/h10-11,13,16,18-22,24-25H,3-9,12,14-15H2,1-2H3,(H,26,27)/b11-10+/t16-,18?,19+,20+,21?,22+/m0/s1
InChIKey	BPNIWRLPDMCZPC-ASUUCAAFSA-N
PubChem Compound ID	73755022
PubChem Substance ID	135651239
Target and Pathway
Target(s)	Prostacyclin receptor	Target Info	Agonist	[534390]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Vascular smooth muscle contraction
	Platelet activation
Pathway Interaction Database	Thromboxane A2 receptor signaling
PathWhiz Pathway	Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin
Reactome	Prostanoid ligand receptors
Reactome	G alpha (s) signalling events
WikiPathways	Prostaglandin Synthesis and Regulation
	GPCRs, Class A Rhodopsin-like
	Small Ligand GPCRs
	Endothelin Pathways
	Platelet homeostasis
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539262	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1965).
Ref 534390	Relaxant actions of nonprostanoid prostacyclin mimetics on human pulmonary artery. J Cardiovasc Pharmacol. 1997 Apr;29(4):525-35.

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Drug Information