Drug General Information
Drug ID	D08XPZ
Former ID	DNC009381
Drug Name	3-Methylquinoline-8-carboxamide
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529894]
Structure		Download 2D MOL 3D MOL
Formula	C11H10N2O
Canonical SMILES	CC1=CN=C2C(=C1)C=CC=C2C(=O)N
InChI	1S/C11H10N2O/c1-7-5-8-3-2-4-9(11(12)14)10(8)13-6-7/h2-6H,1H3,(H2,12,14)
InChIKey	BRQFPNHEOMCVCI-UHFFFAOYSA-N
PubChem Compound ID	25208598
Target and Pathway
Target(s)	Poly [ADP-ribose] polymerase-1	Target Info	Inhibitor	[529894]
KEGG Pathway	Base excision repair
	NF-kappa B signaling pathway
PANTHER Pathway	FAS signaling pathway
Pathway Interaction Database	Integrin-linked kinase signaling
	Caspase Cascade in Apoptosis
	Notch-mediated HES/HEY network
Reactome	Dual Incision in GG-NER
WikiPathways	FAS pathway and Stress induction of HSP regulation
	Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
	Nanoparticle triggered regulated necrosis
	Corticotropin-releasing hormone
References
Ref 529894	J Med Chem. 2009 Feb 12;52(3):868-77.Design, synthesis, and evaluation in vitro of quinoline-8-carboxamides, a new class of poly(adenosine-diphosphate-ribose)polymerase-1 (PARP-1) inhibitor.
Ref 529894	J Med Chem. 2009 Feb 12;52(3):868-77.Design, synthesis, and evaluation in vitro of quinoline-8-carboxamides, a new class of poly(adenosine-diphosphate-ribose)polymerase-1 (PARP-1) inhibitor.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.