Drug Information

Drug General Information
Drug ID
D08SPJ
Former ID
DNC003862
Drug Name
3,4,5,6-Tetrahydrobenzo[c]quinolizin-3-(4aH)-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [525881]
Structure
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2D MOL

3D MOL
Formula
C13H13NO
Canonical SMILES
C1CC2=CC=CC=C2N3C1CC(=O)C=C3
InChI
1S/C13H13NO/c15-12-7-8-14-11(9-12)6-5-10-3-1-2-4-13(10)14/h1-4,7-8,11H,5-6,9H2
InChIKey
LNTWPSKEEYNUKK-UHFFFAOYSA-N
PubChem Compound ID
10442752
Target and Pathway
Target(s) 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Target Info Inhibitor [525881]
BioCyc Pathway Superpathway of steroid hormone biosynthesis
Allopregnanolone biosynthesis
Androgen biosynthesis
KEGG Pathway Steroid hormone biosynthesis
NetPath Pathway IL2 Signaling Pathway
PathWhiz Pathway Androgen and Estrogen Metabolism
Reactome Androgen biosynthesis
References
Ref 525881J Med Chem. 2000 Oct 5;43(20):3718-35.Benzo[c]quinolizin-3-ones: a novel class of potent and selective nonsteroidal inhibitors of human steroid 5alpha-reductase 1.
Ref 525881J Med Chem. 2000 Oct 5;43(20):3718-35.Benzo[c]quinolizin-3-ones: a novel class of potent and selective nonsteroidal inhibitors of human steroid 5alpha-reductase 1.

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