Drug Information
Drug General Information | |||||
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Drug ID |
D08SLS
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Former ID |
DIB018882
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Drug Name |
arpromidine
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [538733] | ||
Structure |
Download2D MOL |
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Formula |
C21H25FN6
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InChI |
InChI=1S/C21H25FN6/c22-17-8-6-16(7-9-17)19(20-5-1-2-11-25-20)10-13-27-21(23)26-12-3-4-18-14-24-15-28-18/h1-2,5-9,11,14-15,19H,3-4,10,12-13H2,(H,24,28)(H3,23,26,27)
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InChIKey |
KZZIVOLMJPSDEP-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Histamine H1 receptor | Target Info | Antagonist | [526569] | |
Histamine H2 receptor | Target Info | Agonist | [527955] | ||
References | |||||
Ref 526569 | Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor. J Pharmacol Exp Ther. 2003 Jun;305(3):1104-15. Epub 2003 Mar 6. | ||||
Ref 527955 | Probing ligand-specific histamine H1- and H2-receptor conformations with NG-acylated Imidazolylpropylguanidines. J Pharmacol Exp Ther. 2006 Apr;317(1):139-46. Epub 2006 Jan 4. |
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