Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08QRO
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| Former ID |
DIB007291
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| Drug Name |
BL-6020
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| Synonyms |
SNT-207707; SNT-207858; SNT-209858; MC4-R antagonists (anorexia), Santhera; MC4-R antagonists (cachexia), Santhera; Melanocortin 4 receptor antagonists (cachexia/anorexia), Santhera; MC4-R antagonists (cachexia/anorexia), Santhera; MC4-R antagonists (cachexia/anorexia), Santhera/ BioLineRx
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| Indication | Cachexia [ICD9: 799.4; ICD10:R64] | Investigative | [1] | ||
| Company |
MyoContract Pharmaceutical Research Ltd
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| Structure |
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Download2D MOL |
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| Canonical SMILES |
Cl.Cl.C1CN(CC1)CCCc1n2cc(C(=O)N(CCC(C)C)CCC(C)C)ccc2nc1<br />c1ccc(cc1)C#N
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| Target and Pathway | |||||
| Target(s) | Melanocortin-4 receptor | Target Info | Antagonist | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Pathway Interaction Database | Syndecan-3-mediated signaling events | ||||
| Reactome | Peptide ligand-binding receptors | ||||
| G alpha (s) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 285). | ||||
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