Drug General Information
Drug ID	D08PKS
Former ID	DNC013288
Drug Name	N-guanyl-1,7-diaminoheptane
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528923]
Structure		Download 2D MOL 3D MOL
Formula	C8H20N4
Canonical SMILES	C(CCCN)CCCN=C(N)N
InChI	1S/C8H20N4/c9-6-4-2-1-3-5-7-12-8(10)11/h1-7,9H2,(H4,10,11,12)
InChIKey	YAOAMZOGXBMLFQ-UHFFFAOYSA-N
PubChem Compound ID	448393
Target and Pathway
Target(s)	Deoxyhypusine synthase	Target Info	Inhibitor	[528923]
BioCyc Pathway	Hypusine biosynthesis
NetPath Pathway	TGF_beta_Receptor Signaling Pathway
WikiPathways	PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
References
Ref 528923	Bioorg Med Chem. 2007 Sep 15;15(18):6200-7. Epub 2007 Jun 14.Modification of eukaryotic initiation factor 5A from Plasmodium vivax by a truncated deoxyhypusine synthase from Plasmodium falciparum: An enzyme with dual enzymatic properties.
Ref 528923	Bioorg Med Chem. 2007 Sep 15;15(18):6200-7. Epub 2007 Jun 14.Modification of eukaryotic initiation factor 5A from Plasmodium vivax by a truncated deoxyhypusine synthase from Plasmodium falciparum: An enzyme with dual enzymatic properties.

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