Drug Information

Drug General Information
Drug ID
D08OUX
Former ID
DNC012501
Drug Name
IODOPRIDE
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533883]
Structure
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2D MOL

3D MOL
Formula
C15H21IN2O2
Canonical SMILES
CCN1CCCC1CNC(=O)C2=C(C=CC(=C2)I)OC
InChI
1S/C15H21IN2O2/c1-3-18-8-4-5-12(18)10-17-15(19)13-9-11(16)6-7-14(13)20-2/h6-7,9,12H,3-5,8,10H2,1-2H3,(H,17,19)/t12-/m0/s1
InChIKey
JHMTYLJMPBFCTD-LBPRGKRZSA-N
PubChem Compound ID
3082754
Target and Pathway
Target(s) D(2) dopamine receptor Target Info Inhibitor [533883]
KEGG Pathway Rap1 signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Alcoholism
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Dopamine receptor mediated signaling pathway
Nicotine pharmacodynamics pathway
Reactome Dopamine receptors
G alpha (i) signalling events
WikiPathways Hypothetical Network for Drug Addiction
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Genes and (Common) Pathways Underlying Drug Addiction
GPCR ligand binding
GPCR downstream signaling
Nicotine Activity on Dopaminergic Neurons
References
Ref 533883J Med Chem. 1993 Jan 22;36(2):221-8.Fluorinated and iodinated dopamine agents: D2 imaging agents for PET and SPECT.
Ref 533883J Med Chem. 1993 Jan 22;36(2):221-8.Fluorinated and iodinated dopamine agents: D2 imaging agents for PET and SPECT.

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