Drug Information

Drug General Information
Drug ID
D08GRF
Former ID
DIB000006
Drug Name
LG-1550
Synonyms
ALRT-1550; ALRT-550; LGD-1550; Pre-Registered; (2E,4E,6E)-7-(3,5-Di-tert-butylphenyl)-3-methylocta-2,4,6-trienoic acid
Drug Type
Small molecular drug
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Discontinued in Phase 2 [539785], [546388]
Company
Ligand Pharmaceuticals
Structure
Download
2D MOL

3D MOL
Formula
C23H32O2
InChI
InChI=1S/C23H32O2/c1-16(12-21(24)25)10-9-11-17(2)18-13-19(22(3,4)5)15-20(14-18)23(6,7)8/h9-15H,1-8H3,(H,24,25)/b10-9+,16-12+,17-11+
InChIKey
JMPZTWDLOGTBPM-OUQSKUGOSA-N
CAS Number
CAS 178600-20-9
PubChem Compound ID
5287705
PubChem Substance ID
7885963, 11041323, 14900311, 39320269, 46392648, 50143800, 103298156, 103948958, 113870258, 135649927, 137184919, 139221749, 231809668, 231809674
Target and Pathway
Target(s) Retinoic acid receptor Target Info Modulator [550887]
References
Ref 539785(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2740).
Ref 546388Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007857)
Ref 550887US patent application no. 2005,0014,729, Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith.

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