Drug General Information
Drug ID	D08FKH
Former ID	DIB014322
Drug Name	KLH-2109
Indication	Endometriosis [ICD9: 617; ICD10:N80]		Phase 2	[523797]
Company	Kissei Pharmaceutical Co Ltd
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Gonadotropin-releasing hormone receptor	Target Info	Agonist	[550310]
KEGG Pathway	Neuroactive ligand-receptor interaction
	GnRH signaling pathway
NetPath Pathway	IL1 Signaling Pathway
	IL2 Signaling Pathway
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome	Hormone ligand-binding receptors
	G alpha (q) signalling events
WikiPathways	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 523797	ClinicalTrials.gov (NCT01533532) A Randomized, Placebo-controlled, Double-blind Study of KLH-2109 in Patients With Endometriosis (2). U.S. National Institutes of Health.
Ref 550310	Clinical pipeline report, company report or official report of Avarx.

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