Drug Information

Drug General Information
Drug ID
D08ERD
Former ID
DIB018083
Drug Name
(R)-5-diphosphomevalonate
Synonyms
mevalonate 5-diphosphate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540048]
Structure
Download
2D MOL
Formula
C6H14O10P2
InChI
InChI=1S/C6H14O10P2/c1-6(9,4-5(7)8)2-3-15-18(13,14)16-17(10,11)12/h9H,2-4H2,1H3,(H,7,8)(H,13,14)(H2,10,11,12)/t6-/m1/s1
InChIKey
SIGQQUBJQXSAMW-ZCFIWIBFSA-N
PubChem Compound ID
439418
PubChem Substance ID
4374, 8145088, 10298332, 24697980, 36883645, 79436129, 103537352, 104620459, 123060236, 126523800, 135651554, 136380761, 136380772, 137220405, 139524400, 229303009, 242943846
Target and Pathway
Target(s) phosphomevalonate kinase Target Info Inhibitor [529070]
References
Ref 540048(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3047).
Ref 529070Functional evaluation of conserved basic residues in human phosphomevalonate kinase. Biochemistry. 2007 Oct 23;46(42):11780-8. Epub 2007 Sep 29.

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