Drug General Information
Drug ID	D08DFU
Former ID	DIB008165
Drug Name	CMX-157
Synonyms	Hexadecyloxypropyl tenofovir
Drug Type	Small molecular drug
Indication	Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26]		Phase 1	[522964]
Company	Chimerix
Structure		Download 2D MOL 3D MOL
Formula	C28H52N5O5P
Canonical SMILES	P(=O)(O)(CO[C@@H](Cn1c2ncnc(c2nc1)N)C)OCCCOCCCCCCCCCCCC<br />CCCC
PubChem Compound ID	56841860
Target and Pathway
Target(s)	HIV reverse transcriptase	Target Info	Inhibitor	[544301]
References
Ref 522964	ClinicalTrials.gov (NCT01080820) A Safety, Tolerability and Pharmacokinetic Study of a Single Dose of CMX157 in Healthy Volunteers. U.S. National Institutes of Health.
Ref 544301	Practical Considerations For Developing Nucleoside Reverse Transcriptase Inhibitors. Drug Discov Today Technol. 2012 Autumn; 9(3): e183-e193.

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