Drug Information

Drug General Information
Drug ID
D07VCG
Former ID
DIB003219
Drug Name
Anti-VEGFR 3 mab
Synonyms
Anti-VEGFR 3 mAb (undisclosed indication); Anti-VEGFR 3 mAb (undisclosed indication), PharmAbcine; Vascular endothelial growth factor receptor 3 inhibitor (mAb, undisclosed indication), PharmAbcine
Drug Type
Monoclonal antibody
Indication Discovery agent Investigative [543500]
Company
PharmAbcine
Target and Pathway
Target(s) Vascular endothelial growth factor receptor 3 Target Info Inhibitor [543500]
KEGG Pathway Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Focal adhesion
NetPath Pathway TNFalpha Signaling Pathway
Pathway Interaction Database VEGF and VEGFR signaling network
VEGFR3 signaling in lymphatic endothelium
Reactome VEGF binds to VEGFR leading to receptor dimerization
WikiPathways Signaling by VEGF
References
Ref 543500(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1814).
Ref 543500(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1814).

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