Drug General Information
Drug ID	D07VAI
Former ID	DIB004529
Drug Name	ALZ-801
Indication	Alzheimer disease [ICD9: 331; ICD10:G30]		Phase 1	[1]
Company	Alzheon
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Amyloid beta A4 protein	Target Info	Inhibitor	[2]
KEGG Pathway	Notch signaling pathway
	Alzheimer's disease
Reactome	Nuclear signaling by ERBB4
	Degradation of the extracellular matrix
	Regulated proteolysis of p75NTR
	NRIF signals cell death from the nucleus
	Activated NOTCH1 Transmits Signal to the Nucleus
	Constitutive Signaling by NOTCH1 PEST Domain Mutants
	Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
	EPH-ephrin mediated repulsion of cells
WikiPathways	Notch Signaling Pathway
	Signaling by ERBB4
	Signaling by NOTCH3
	Signaling by NOTCH4
	Signaling by NOTCH1
	Signaling by NOTCH2
	Notch Signaling Pathway
	Alzheimers Disease
	Signalling by NGF
References
REF 1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800040203)
REF 2	Oral Clinical Candidate ALZ-801 in Alzheon's pipeline. 2012.

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