Drug General Information
Drug ID
D07PLK
Former ID
DIB016402
Drug Name
WIN-64821
Synonyms
Q-20547A
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Terminated [546013]
Company
Sterling Winthrop Products Inc
Structure
Download
2D MOL

3D MOL

Formula
C40H36N6O4
Canonical SMILES
[C@]12([C@]34[C@@H](N5[C@@H](C4)C(=O)N[C@H](C5=O)Cc4ccc<br />cc4)Nc4c3cccc4)[C@@H](N3[C@@H](C2)C(=O)N[C@H](C3=O)Cc2c<br />cccc2)Nc2c1cccc2
CAS Number
CAS 150881-27-9
PubChem Compound ID
Target and Pathway
Target(s) Substance-P receptor Target Info Antagonist [533611]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Measles
PANTHER Pathway CCKR signaling map ST
Reactome G alpha (q) signalling events
WikiPathways SIDS Susceptibility Pathways
Gastrin-CREB signalling pathway via PKC and MAPK
Spinal Cord Injury
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 546013Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005879)
Ref 533611WIN 64821, a novel neurokinin antagonist produced by an Aspergillus sp. II. Biological activity. J Antibiot (Tokyo). 1994 Apr;47(4):399-410.

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