Drug General Information
Drug ID
D07PAO
Former ID
DAP001524
Drug Name
Sulphadoxine
Synonyms
Fanasil; Fanzil; Orthosulfin; SULFADOXINE; Solfadossina; Sulfadoxin; Sulfadoxina; Sulfadoxinum; Sulformethoxine; Sulformetoxine; Sulforthomidine; Sulphormethoxine; Sulphormetoxin; Sulphorthodimethoxine; Solfadossina [DCIT]; WR 4073; WR 4873; Ro 4-4393; Sulfadoxina [INN-Spanish]; Sulfadoxinum [INN-Latin]; Ro-4-4393; Sanasil: Sulfadoxine: Sulformetoxin; Sulfadoxine (JAN/USP/INN); Sulfadoxine [USAN:INN:BAN:JAN]; N1-(5,6-Dimethoxy-4-pyrimidinyl)sulfanilamide; N'-(5,6-Dimethoxy-4-pyrimidyl)sulfanilamide; N(sup 1)-(5,6-Dimethoxy-4-pyrimidinyl)sulfanilamide; 4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide; 4-Sulfanilamido-5,6-dimethoxypyrimidine; 4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide; 4-amino-N-[5,6-bis(methyloxy)pyrimidin-4-yl]benzenesulfonamide; 6-(4-Aminobenzenesulfonamido)-4,5-dimethoxypyrimidine
Drug Type
Small molecular drug
Indication Malaria [ICD10:B54] Approved [536602]
Structure
Download
2D MOL

3D MOL

Formula
C12H14N4O4S
Canonical SMILES
COC1=C(N=CN=C1OC)NS(=O)(=O)C2=CC=C(C=C2)N
InChI
1S/C12H14N4O4S/c1-19-10-11(14-7-15-12(10)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
InChIKey
PJSFRIWCGOHTNF-UHFFFAOYSA-N
CAS Number
CAS 2447-57-6
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:9329
Target and Pathway
Target(s) Dihydropteroate synthetase Target Info Binder [536602]
References
Ref 536602The fight against drug-resistant malaria: novel plasmodial targets and antimalarial drugs. Curr Med Chem. 2008;15(2):161-71.
Ref 536602The fight against drug-resistant malaria: novel plasmodial targets and antimalarial drugs. Curr Med Chem. 2008;15(2):161-71.

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