| Drug General Information |
| Drug ID |
D07ODE
|
| Former ID |
DNC002920
|
| Drug Name |
N-phenyl-1H-pyrazole-3-carboxamide
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C10H9N3O
|
| Canonical SMILES |
C1=CC=C(C=C1)NC(=O)C2=CC=NN2
|
| InChI |
1S/C10H9N3O/c14-10(9-6-7-11-13-9)12-8-4-2-1-3-5-8/h1-7H,(H,11,13)(H,12,14)
|
| InChIKey |
WMZYZYFPPQOFKY-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
4768633, 5683418, 9283313, 11221417, 14738661, 24339399, 44865547, 47868331, 50096499, 56269587, 56385376, 71901321, 76408906, 88707638, 92240285, 99444606, 103644612, 104868996, 109870981, 118124107, 121313967, 124535994, 124773311, 129605019, 136306373, 142699714, 160969189, 167040171, 170481362, 178109694, 179197077, 181811294, 223362221, 225230247, 226409411, 238370627, 249099542, 249521751, 252455912
|
| Target and Pathway |
| Target(s) |
Cell division protein kinase 2 |
Target Info |
Inhibitor |
[1]
|
|---|
|
KEGG Pathway
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FoxO signaling pathway
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Cell cycle
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Oocyte meiosis
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p53 signaling pathway
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PI3K-Akt signaling pathway
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Progesterone-mediated oocyte maturation
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Hepatitis B
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Measles
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Herpes simplex infection
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Epstein-Barr virus infection
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Pathways in cancer
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Viral carcinogenesis
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Prostate cancer
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Small cell lung cancer
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NetPath Pathway
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TCR Signaling Pathway
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PANTHER Pathway
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p53 pathway
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p53 pathway feedback loops 2
|
|
Pathway Interaction Database
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Regulation of nuclear SMAD2/3 signaling
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Signaling events mediated by PRL
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p73 transcription factor network
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E2F transcription factor network
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ATR signaling pathway
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mTOR signaling pathway
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IL2-mediated signaling events
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FoxO family signaling
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FOXM1 transcription factor network
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BARD1 signaling events
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p53 pathway
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Regulation of retinoblastoma protein
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Reactome
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G0 and Early G1
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Activation of ATR in response to replication stress
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Regulation of APC/C activators between G1/S and early anaphase
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SCF(Skp2)-mediated degradation of p27/p21
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Senescence-Associated Secretory Phenotype (SASP)
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DNA Damage/Telomere Stress Induced Senescence
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Processing of DNA double-strand break ends
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G2 Phase
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Orc1 removal from chromatin
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Cyclin E associated events during G1/S transition
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Cyclin A/B1 associated events during G2/M transition
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p53-Dependent G1 DNA Damage Response
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Cyclin A:Cdk2-associated events at S phase entry
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Meiotic recombination
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Factors involved in megakaryocyte development and platelet production
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WikiPathways
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DNA Damage Response
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ID signaling pathway
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DNA Replication
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G1 to S cell cycle control
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M/G1 Transition
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S Phase
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Meiotic Recombination
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Aryl Hydrocarbon Receptor
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ATM Signaling Pathway
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Retinoblastoma (RB) in Cancer
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Spinal Cord Injury
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Integrated Pancreatic Cancer Pathway
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Oncostatin M Signaling Pathway
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Prostate Cancer
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Signaling Pathways in Glioblastoma
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TSH signaling pathway
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Integrated Breast Cancer Pathway
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Integrated Cancer pathway
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Synthesis of DNA
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Regulation of DNA replication
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Mitotic G2-G2/M phases
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Mitotic G1-G1/S phases
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Factors involved in megakaryocyte development and platelet production
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Cell Cycle
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APC/C-mediated degradation of cell cycle proteins
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Cell Cycle Checkpoints
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miRNA Regulation of DNA Damage Response
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| References |
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
|---|
